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ErbB3/HER3 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506813
TypePolyclonal Antibodies
HostRabbit
Positive control293T, MCF7, A-431, Mouse liver
IsotypeIgG
SummaryThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 20-285 of human ErbB3/HER3 (NP_001973.2).
PurificationAffinity purification
Gene ID2065
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameERBB3; ErbB-3; HER3; LCCS2; MDA-BF-1; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3
Conjugated Antibody
This product is also available conjugated. Format: E45R17595N-Conjugate. Price: $485 / Size: 100μl.
E45R17595N-FITC$485 / 100μlE45R17595N-Biotin$485 / 100μlE45R17595N-HRP$485 / 100μlE45R17595N-AP$485 / 100μlE45R17595N-AF350$485 / 100μlE45R17595N-AF405M$485 / 100μlE45R17595N-AF488$485 / 100μlE45R17595N-AF514$485 / 100μlE45R17595N-AF532$485 / 100μlE45R17595N-AF555$485 / 100μlE45R17595N-AF568$485 / 100μlE45R17595N-AF405S$485 / 100μlE45R17595N-AF405L$485 / 100μlE45R17595N-AF546$485 / 100μlE45R17595N-AF594$485 / 100μlE45R17595N-AF610$485 / 100μlE45R17595N-AF635$485 / 100μlE45R17595N-AF647$485 / 100μlE45R17595N-AF680$485 / 100μlE45R17595N-AF700$485 / 100μlE45R17595N-AF750$485 / 100μlE45R17595N-AF790$485 / 100μlE45R17595N-APC$485 / 100μlE45R17595N-PE$485 / 100μlE45R17595N-Cy3$485 / 100μlE45R17595N-Cy5$485 / 100μlE45R17595N-Cy5.5$485 / 100μlE45R17595N-Cy7$485 / 100μlE45R17595N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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