Product Information
Cite ID#EN5506806
TypePolyclonal Antibodies
HostRabbit
Positive controlU-251MG, HeLa, Mouse kidney, 293T, NIH/3T3, MCF7, A-549, Mouse heart, Mouse lung
IsotypeIgG
SummaryThis gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.