Product Information
Cite ID#EN5506707
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human Caspase-7 (NP_001218.1).
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionIHC 1:50 - 1:100
IP 1:50 - 1:100
All Names
AlternameCASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; caspase-7; Casp7