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NUP98 Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506695
TypePolyclonal Antibodies
HostRabbit
Positive controlA-549, LO2, HeLa, Jurkat, HL-60
IsotypeIgG
SummaryNuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 621-920 of human NUP98 (NP_624357.1).
PurificationAffinity purification
Gene ID4928
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameNUP98; ADIR2; NUP196; NUP96
Conjugated Antibody
This product is also available conjugated. Format: E45R17467N-Conjugate. Price: $485 / Size: 100μl.
E45R17467N-FITC$485 / 100μlE45R17467N-Biotin$485 / 100μlE45R17467N-HRP$485 / 100μlE45R17467N-AP$485 / 100μlE45R17467N-AF350$485 / 100μlE45R17467N-AF405M$485 / 100μlE45R17467N-AF488$485 / 100μlE45R17467N-AF514$485 / 100μlE45R17467N-AF532$485 / 100μlE45R17467N-AF555$485 / 100μlE45R17467N-AF568$485 / 100μlE45R17467N-AF405S$485 / 100μlE45R17467N-AF405L$485 / 100μlE45R17467N-AF546$485 / 100μlE45R17467N-AF594$485 / 100μlE45R17467N-AF610$485 / 100μlE45R17467N-AF635$485 / 100μlE45R17467N-AF647$485 / 100μlE45R17467N-AF680$485 / 100μlE45R17467N-AF700$485 / 100μlE45R17467N-AF750$485 / 100μlE45R17467N-AF790$485 / 100μlE45R17467N-APC$485 / 100μlE45R17467N-PE$485 / 100μlE45R17467N-Cy3$485 / 100μlE45R17467N-Cy5$485 / 100μlE45R17467N-Cy5.5$485 / 100μlE45R17467N-Cy7$485 / 100μlE45R17467N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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