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VHL Rabbit pAb

Human, Mouse, Rat
WB (human kidney cancer cells, LNCaP, Homo sapiens, Danio rerio)
IF (Homo sapiens)
P40337
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505472
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa, Mouse brain, Rat brain
IsotypeIgG
SummaryVon Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human VHL (NP_937799.1).
PurificationAffinity purification
Gene ID7428
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameVHL; HRCA1; RCA1; VHL1; pVHL; PVHL

Conjugated Antibody

This product is also available conjugated. Format: E45R17432N-Conjugate. Price: $485 / Size: 100μl.

E45R17432N-FITC$485 / 100μlE45R17432N-Biotin$485 / 100μlE45R17432N-HRP$485 / 100μlE45R17432N-AP$485 / 100μlE45R17432N-AF350$485 / 100μlE45R17432N-AF405M$485 / 100μlE45R17432N-AF488$485 / 100μlE45R17432N-AF514$485 / 100μlE45R17432N-AF532$485 / 100μlE45R17432N-AF555$485 / 100μlE45R17432N-AF568$485 / 100μlE45R17432N-AF405S$485 / 100μlE45R17432N-AF405L$485 / 100μlE45R17432N-AF546$485 / 100μlE45R17432N-AF594$485 / 100μlE45R17432N-AF610$485 / 100μlE45R17432N-AF635$485 / 100μlE45R17432N-AF647$485 / 100μlE45R17432N-AF680$485 / 100μlE45R17432N-AF700$485 / 100μlE45R17432N-AF750$485 / 100μlE45R17432N-AF790$485 / 100μlE45R17432N-APC$485 / 100μlE45R17432N-PE$485 / 100μlE45R17432N-Cy3$485 / 100μlE45R17432N-Cy5$485 / 100μlE45R17432N-Cy5.5$485 / 100μlE45R17432N-Cy7$485 / 100μlE45R17432N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.