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ARL2 Antibody (Center)
Datasheet   

  • Catalog Number:

    E45R15053G-1

  • Amount:

    100 µl

  • Cite ID#:

    EN5481842

  • Price:

    395$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H

  • Immunogen:

    This ARL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the Central region of human ARL2.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    ARL2

  • Gene ID:

    402

  • Swiss-Prot No.:

    P36404

  • Function:

    Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle (PubMed:10831612, PubMed:16525022, PubMed:18234692, PubMed:18588884, PubMed:20740604). Also regulates mitochondrial integrity and function (PubMed:30945270).

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    WB

  • Dilution:

    WB--1:2000
    WB--1:1000

  • Altername:

    ADP-ribosylation factor-like protein 2, ARL2

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ARL2 Antibody (Center) | EnoGene Biotech Co. Ltd