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ErbB4/HER4 Rabbit mAb
Mouse, Rat
$458/ 100 µl
QuantityTotal: $458
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Product Information
Cite ID#EN5520374
TypeMonoclonal Antibodies
HostRabbit
Positive controlMouse brain, Rat brain
IsotypeIgG
SummaryThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human ErbB4/HER4
PurificationAffinity purification
Gene ID2066
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameALS19; HER4; p180erbB4; ERBB4; HER4/ErbB4
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