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[KO Validated] active + pro Caspase-3 Rabbit mAb
Human, Mouse, Rat
WB (Mus musculus, Sanghuangporus vaninii, Homo sapiens, Rattus norvegicus, Apocynum venetum leaf, Giardia duodenalis)
$526/ 100 µl
QuantityTotal: $526
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Product Information
Cite ID#EN5520357
TypeMonoclonal Antibodies
HostRabbit
Positive controlJurkat, Mouse lung, Mouse liver, NIH/3T3, Rat spleen, Rat liver, 293T, L929
IsotypeIgG
SummaryThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price526$
ImmunogenA synthesized peptide derived from human active + pro Caspase-3.
PurificationAffinity purification
Gene ID836
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameCPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3
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