Product Information
Cite ID#EN5520348
TypeMonoclonal Antibodies
HostRabbit
Positive controlHeLa, 293T, HepG2, Rat liver, Rat brain, Mouse liver
IsotypeIgG
SummaryThis gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.