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Phospho-JNK1/2/3-T183/T183/T221 Rabbit mAb
Human, Mouse, Rat
WB (Mus musculus, Homo sapiens, Rattus norvegicus)
IF (Rattus norvegicus)
IHC (Mus musculus)
IF (Rattus norvegicus)
IHC (Mus musculus)
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5520347
TypePhosphorylated Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenA phospho specific peptide corresponding to residues surrounding T183/T183/T221 of human JNK1/2/3
PurificationAffinity purification
Gene ID5599/5601/5602
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameJNK1/JNK2/JNK3
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