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Phospho-eIF2α-S51 Rabbit mAb
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5520343
TypePhosphorylated Antibodies
HostRabbit
Positive controlHeLa, NIH/3T3
IsotypeIgG
SummaryThe translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenA synthesized peptide derived from human Phospho-EIF2S1 (S51).
PurificationAffinity purification
Gene ID1965
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameEIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A; EIF2S1
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