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N6-methyladenosine / m6A Rabbit mAb
Human, Mouse, Rat, Other (Wide Range)
DB (Homo sapiens, Rattus norvegicus) MeRIP-qPCR (Homo sapiens)
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5520329
TypeOther Modified Antibodies
HostRabbit
Positive controlArabidopsis
IsotypeIgG
SummaryDiscovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenChemical compounds corresponding to N6-methyladenosine / m6A.
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionDB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameN6-methyladenosine; m6A
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