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Glucocorticoid Receptor Rabbit mAb
$458/ 100 µl
QuantityTotal: $458
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Product Information
Cite ID#EN5520233
TypeMonoclonal Antibodies
HostRabbit
Positive controlU-251MG, OVCAR3, HepG2, HeLa, Mouse liver, Mouse kidney, Rat liver
IsotypeIgG
SummaryThis gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human GR.
PurificationAffinity purification
Gene ID2908
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IP 1:50 - 1:200
IP 1:50 - 1:200
All Names
AlternameGCCR; GCR; GCRST; GR; GRL; NR3C1
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