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CD40 Rabbit mAb
Human
$614/ 100 µl
QuantityTotal: $614
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5520083
TypeMonoclonal Antibodies
HostRabbit
IsotypeIgG
SummaryThis gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
FormLiquid
Storage BufferBuffer: PBS with 0.02% thimerosal, pH7.3.
Price614$
ImmunogenRecombinant protein of human CD40
PurificationAffinity purification
Gene ID958
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionELISA 1:500 - 1:2000
WB 1:500 - 1:2000
FC 1:50 - 1:200
IF 1:50 - 1:200
WB 1:500 - 1:2000
FC 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameCD40; Bp50; CDW40; TNFRSF5; p50
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