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CDKN1B/p27KIP1 Rabbit mAb

Human, Mouse, Rat
P46527
$458/ 100 µl
Quantity
Total: $458

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Product Information

Cite ID#EN5519979
TypeMonoclonal Antibodies
HostRabbit
Positive controlHepG2, 293T, C6, Mouse lung, Rat lung, HeLa
IsotypeIgG
SummaryThis gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human CDKN1B/p27KIP1
PurificationAffinity purification
Gene ID1027
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

All Names

AlternameCDKN1B; CDKN4; KIP1; MEN1B; MEN4; P27KIP1; p27 KIP 1
CDKN1B/p27KIP1 Rabbit mAb | EnoGene Biotech Co. Ltd