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Phospho-RB-S780 Rabbit mAb
Human, Mouse, Rat
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5519922
TypePhosphorylated Antibodies
HostRabbit
Positive controlC6
IsotypeIgG
SummaryThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenA phospho synthetic peptide corresponding to residues surrounding S780 of human RB.
PurificationAffinity purification
Gene ID5925
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
All Names
AlternameOSRC; PPP1R130; RB; p105-Rb; pRb; pp110; RB1; Rb
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