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MC1 Receptor Rabbit mAb

Human, Mouse, Rat
Q01726
$526/ 100 µl
Quantity
Total: $526

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5519761
TypeMonoclonal Antibodies
HostRabbit
Positive controlA-549, A375, C6, MCF7, Mouse kidney
IsotypeIgG
SummaryThis intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price526$
ImmunogenA synthesized peptide derived from human MC1 Receptor
PurificationAffinity purification
Gene ID4157
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameCMM5; MSH-R; SHEP2
MC1 Receptor Rabbit mAb | EnoGene Biotech Co. Ltd