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Thioredoxin reductase 1 Rabbit mAb
Human, Mouse, Rat
$458/ 100 µl
QuantityTotal: $458
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Product Information
Cite ID#EN5519584
TypeMonoclonal Antibodies
HostRabbit
Positive controlHeLa, A-549, MCF7, Jurkat, Mouse brain, Mouse heart, Mouse thymus, Rat liver, Rat kidney
IsotypeIgG
SummaryThis gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human Thioredoxin reductase 1 (Thioredoxin reductase 1 (TXNRD1 ) )
PurificationAffinity purification
Gene ID7296
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameGRIM-12; TR; TR1; TRXR1; TXNR
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