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Phospho-Crk p38-Y221 Rabbit mAb
Human, Mouse, Rat
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5519287
TypePhosphorylated Antibodies
HostRabbit
Positive controlNIH/3T3, C6
IsotypeIgG
SummaryThis gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenA phospho specific peptide corresponding to residues surrounding Y221 of human Crk p38
PurificationAffinity purification
Gene ID1398
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameCRKII; p38
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