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Phospho-Chk1-S296 Rabbit mAb
Human
$614/ 100 µl
QuantityTotal: $614
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Product Information
Cite ID#EN5519275
TypePhosphorylated Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummaryThe protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price614$
ImmunogenA phospho specific peptide corresponding to residues surrounding S296 of human Chk1
PurificationAffinity purification
Gene ID1111
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameCHK1
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