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RCC1 Rabbit mAb
Human, Mouse, Rat
$458/ 100 µl
QuantityTotal: $458
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Product Information
Cite ID#EN5519196
TypeMonoclonal Antibodies
HostRabbit
Positive controlHeLa, Raji, SH-SY5Y, Mouse spleen, Mouse thymus, Rat testis
IsotypeIgG
SummaryGuanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human RCC1
PurificationAffinity purification
Gene ID1104
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
All Names
AlternameCHC1; RCC1-I; SNHG3-RCC1
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