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Legumain (LGMN) Rabbit mAb

Human, Mouse
Q99538
$458/ 100 µl
Quantity
Total: $458

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Product Information

Cite ID#EN5519175
TypeMonoclonal Antibodies
HostRabbit
Positive control293T, HepG2, MCF7, Mouse brain, Mouse spleen, Mouse kidney
IsotypeIgG
SummaryThis gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human Legumain (LGMN) (LGMN)
PurificationAffinity purification
Gene ID5641
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameAEP; LGMN1; PRSC1
Legumain (LGMN) Rabbit mAb | EnoGene Biotech Co. Ltd