Product Information
Cite ID#EN5519148
TypeMonoclonal Antibodies
HostRabbit
Positive control293T, K-562, U-87MG, Mouse lung, Mouse testis, Mouse brain, Rat brain
IsotypeIgG
SummaryThis gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.