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α-Actinin-4 Rabbit mAb
Human, Mouse, Rat
$475/ 100 µl
QuantityTotal: $475
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5519140
TypeMonoclonal Antibodies
HostRabbit
Positive controlHeLa, 293T, Jurkat, Mouse brain, Mouse spleen, Rat lung
IsotypeIgG
SummaryAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price475$
ImmunogenA synthesized peptide derived from human α-Actinin-4
PurificationAffinity purification
Gene ID81
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
All Names
AlternameACTININ-4; FSGS; FSGS1
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