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p53 DINP1 Rabbit mAb

Human, Mouse, Rat
Q96A56
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518870
TypeMonoclonal Antibodies
HostRabbit
Positive controlHepG2, A-549, BxPC-3, RAW264.7, C6, Mouse lung, Mouse liver, Rat lung
IsotypeIgG
SummaryAntiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human p53 DINP1
PurificationAffinity purification
Gene ID94241
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameSIP; TP53DINP1; TP53INP1A; TP53INP1B; Teap; p53DINP1

Conjugated Antibody

This product is also available conjugated. Format: E45R11624N-Conjugate. Price: $485 / Size: 100μl.

E45R11624N-FITC$485 / 100μlE45R11624N-Biotin$485 / 100μlE45R11624N-HRP$485 / 100μlE45R11624N-AP$485 / 100μlE45R11624N-AF350$485 / 100μlE45R11624N-AF405M$485 / 100μlE45R11624N-AF488$485 / 100μlE45R11624N-AF514$485 / 100μlE45R11624N-AF532$485 / 100μlE45R11624N-AF555$485 / 100μlE45R11624N-AF568$485 / 100μlE45R11624N-AF405S$485 / 100μlE45R11624N-AF405L$485 / 100μlE45R11624N-AF546$485 / 100μlE45R11624N-AF594$485 / 100μlE45R11624N-AF610$485 / 100μlE45R11624N-AF635$485 / 100μlE45R11624N-AF647$485 / 100μlE45R11624N-AF680$485 / 100μlE45R11624N-AF700$485 / 100μlE45R11624N-AF750$485 / 100μlE45R11624N-AF790$485 / 100μlE45R11624N-APC$485 / 100μlE45R11624N-PE$485 / 100μlE45R11624N-Cy3$485 / 100μlE45R11624N-Cy5$485 / 100μlE45R11624N-Cy5.5$485 / 100μlE45R11624N-Cy7$485 / 100μlE45R11624N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

p53 DINP1 Rabbit mAb | EnoGene Biotech Co. Ltd