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FMO3 Rabbit mAb
Human, Mouse, Rat
$458/ 100 µl
QuantityTotal: $458
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518864
TypeMonoclonal Antibodies
HostRabbit
Positive controlMouse lung, Mouse liver, Mouse kidney, Rat liver, Rat kidney
IsotypeIgG
SummaryFlavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenRecombinant protein of human FMO3.
PurificationAffinity purification
Gene ID2328
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameFMO3; FMOII; TMAU; dJ127D3.1; flavin containing monooxygenase 3
Conjugated Antibody
This product is also available conjugated. Format: E45R11618N-Conjugate. Price: $485 / Size: 100μl.
E45R11618N-FITC$485 / 100μlE45R11618N-Biotin$485 / 100μlE45R11618N-HRP$485 / 100μlE45R11618N-AP$485 / 100μlE45R11618N-AF350$485 / 100μlE45R11618N-AF405M$485 / 100μlE45R11618N-AF488$485 / 100μlE45R11618N-AF514$485 / 100μlE45R11618N-AF532$485 / 100μlE45R11618N-AF555$485 / 100μlE45R11618N-AF568$485 / 100μlE45R11618N-AF405S$485 / 100μlE45R11618N-AF405L$485 / 100μlE45R11618N-AF546$485 / 100μlE45R11618N-AF594$485 / 100μlE45R11618N-AF610$485 / 100μlE45R11618N-AF635$485 / 100μlE45R11618N-AF647$485 / 100μlE45R11618N-AF680$485 / 100μlE45R11618N-AF700$485 / 100μlE45R11618N-AF750$485 / 100μlE45R11618N-AF790$485 / 100μlE45R11618N-APC$485 / 100μlE45R11618N-PE$485 / 100μlE45R11618N-Cy3$485 / 100μlE45R11618N-Cy5$485 / 100μlE45R11618N-Cy5.5$485 / 100μlE45R11618N-Cy7$485 / 100μlE45R11618N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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