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FGL1 Rabbit mAb

E45R11543NDatasheetCOAMSDS
Human
Q08830
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518789
TypeMonoclonal Antibodies
HostRabbit
Positive controlHepG2
IsotypeIgG
SummaryFibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. The FGL1-LAG-3 pathway maybe an important immune evasion mechanism and could contribute to current cancer immunotherapy efforts for several reasons. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner. FGL1 is highly produced by human cancer cells, and elevated FGL1 in the plasma of cancer patients is associated with a poor prognosis and resistance to anti-PD-1/B7-H1 therapy
FormLiquid
Storage BufferBuffer: PBS with 0.09% sodium azide, 50% glycerol, pH7.4.
Price458$
ImmunogenRecombinant protein of human FGL-1 Full length.
PurificationAffinity purification
Gene ID2267
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000

All Names

AlternameFGL1; HFREP1; HP-041; LFIRE-1; LFIRE1
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R11543N-Conjugate. Price: $485 / Size: 100μl.

E45R11543N-FITC$485 / 100μlE45R11543N-Biotin$485 / 100μlE45R11543N-HRP$485 / 100μlE45R11543N-AP$485 / 100μlE45R11543N-AF350$485 / 100μlE45R11543N-AF405M$485 / 100μlE45R11543N-AF488$485 / 100μlE45R11543N-AF514$485 / 100μlE45R11543N-AF532$485 / 100μlE45R11543N-AF555$485 / 100μlE45R11543N-AF568$485 / 100μlE45R11543N-AF405S$485 / 100μlE45R11543N-AF405L$485 / 100μlE45R11543N-AF546$485 / 100μlE45R11543N-AF594$485 / 100μlE45R11543N-AF610$485 / 100μlE45R11543N-AF635$485 / 100μlE45R11543N-AF647$485 / 100μlE45R11543N-AF680$485 / 100μlE45R11543N-AF700$485 / 100μlE45R11543N-AF750$485 / 100μlE45R11543N-AF790$485 / 100μlE45R11543N-APC$485 / 100μlE45R11543N-PE$485 / 100μlE45R11543N-Cy3$485 / 100μlE45R11543N-Cy5$485 / 100μlE45R11543N-Cy5.5$485 / 100μlE45R11543N-Cy7$485 / 100μlE45R11543N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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FGL1 Rabbit mAb | EnoGene Biotech Co. Ltd