World supplier of antibodies, antigens and kits since 2007
Other Products

53BP1 Rabbit mAb

Human, Mouse
Q12888
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518779
TypeMonoclonal Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryDouble-strand break (DSB repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR during antibody genesis. Plays a key role in the repair of double-strand DNA breaks (DSBs in response to DNA damage by promoting non-homologous end joining (NHEJ-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR repair protein BRCA1. In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs sites. Recruited to DSBs sites by recognizing and binding histone H2A monoubiquitinated at 'Lys-15' (H2AK15Ub and histone H4 dimethylated at 'Lys-20' (H4K20me2, two histone marks that are present at DSBs sites. Required for immunoglobulin class-switch recombination (CSR during antibody genesis, a process that involves the generation of DNA DSBs. Participates in the repair and the orientation of the broken DNA ends during CSR (By similarity. In contrast, it is not required for classic NHEJ and V(DJ recombination (By similarity. Promotes NHEJ of dysfunctional telomeres via interaction with PAXIP1.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human 53BP1
PurificationAffinity purification
Gene ID7158
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

Altername53BP1; TDRD30; TP53; p202; p53BP1

Conjugated Antibody

This product is also available conjugated. Format: E45R11533N-Conjugate. Price: $485 / Size: 100μl.

E45R11533N-FITC$485 / 100μlE45R11533N-Biotin$485 / 100μlE45R11533N-HRP$485 / 100μlE45R11533N-AP$485 / 100μlE45R11533N-AF350$485 / 100μlE45R11533N-AF405M$485 / 100μlE45R11533N-AF488$485 / 100μlE45R11533N-AF514$485 / 100μlE45R11533N-AF532$485 / 100μlE45R11533N-AF555$485 / 100μlE45R11533N-AF568$485 / 100μlE45R11533N-AF405S$485 / 100μlE45R11533N-AF405L$485 / 100μlE45R11533N-AF546$485 / 100μlE45R11533N-AF594$485 / 100μlE45R11533N-AF610$485 / 100μlE45R11533N-AF635$485 / 100μlE45R11533N-AF647$485 / 100μlE45R11533N-AF680$485 / 100μlE45R11533N-AF700$485 / 100μlE45R11533N-AF750$485 / 100μlE45R11533N-AF790$485 / 100μlE45R11533N-APC$485 / 100μlE45R11533N-PE$485 / 100μlE45R11533N-Cy3$485 / 100μlE45R11533N-Cy5$485 / 100μlE45R11533N-Cy5.5$485 / 100μlE45R11533N-Cy7$485 / 100μlE45R11533N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.