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NCF4/p40-phox Rabbit mAb

E45R11360NDatasheetCOAMSDS
Human, Mouse
Q15080
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518606
TypeMonoclonal Antibodies
HostRabbit
Positive controlTHP-1, Mouse thymus
IsotypeIgG
SummaryThe protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human NCF4/p40-phox.
PurificationAffinity purification
Gene ID4689
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:200

All Names

AlternameNCF4; CGD3; NCF; P40PHOX; SH3PXD4; neutrophil cytosol factor 4
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R11360N-Conjugate. Price: $485 / Size: 100μl.

E45R11360N-FITC$485 / 100μlE45R11360N-Biotin$485 / 100μlE45R11360N-HRP$485 / 100μlE45R11360N-AP$485 / 100μlE45R11360N-AF350$485 / 100μlE45R11360N-AF405M$485 / 100μlE45R11360N-AF488$485 / 100μlE45R11360N-AF514$485 / 100μlE45R11360N-AF532$485 / 100μlE45R11360N-AF555$485 / 100μlE45R11360N-AF568$485 / 100μlE45R11360N-AF405S$485 / 100μlE45R11360N-AF405L$485 / 100μlE45R11360N-AF546$485 / 100μlE45R11360N-AF594$485 / 100μlE45R11360N-AF610$485 / 100μlE45R11360N-AF635$485 / 100μlE45R11360N-AF647$485 / 100μlE45R11360N-AF680$485 / 100μlE45R11360N-AF700$485 / 100μlE45R11360N-AF750$485 / 100μlE45R11360N-AF790$485 / 100μlE45R11360N-APC$485 / 100μlE45R11360N-PE$485 / 100μlE45R11360N-Cy3$485 / 100μlE45R11360N-Cy5$485 / 100μlE45R11360N-Cy5.5$485 / 100μlE45R11360N-Cy7$485 / 100μlE45R11360N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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NCF4/p40-phox Rabbit mAb | EnoGene Biotech Co. Ltd