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Niemann Pick C1 Rabbit mAb

E45R11316NDatasheetCOAMSDS
Human, Mouse, Rat
O15118
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518562
TypeMonoclonal Antibodies
HostRabbit
Positive controlA-549, Mouse liver, Rat lung
IsotypeIgG
SummaryThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA synthesized peptide derived from human Niemann Pick C1.
PurificationAffinity purification
Gene ID4864
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameNPC1; NPC; Niemann-Pick C1 protein
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R11316N-Conjugate. Price: $485 / Size: 100μl.

E45R11316N-FITC$485 / 100μlE45R11316N-Biotin$485 / 100μlE45R11316N-HRP$485 / 100μlE45R11316N-AP$485 / 100μlE45R11316N-AF350$485 / 100μlE45R11316N-AF405M$485 / 100μlE45R11316N-AF488$485 / 100μlE45R11316N-AF514$485 / 100μlE45R11316N-AF532$485 / 100μlE45R11316N-AF555$485 / 100μlE45R11316N-AF568$485 / 100μlE45R11316N-AF405S$485 / 100μlE45R11316N-AF405L$485 / 100μlE45R11316N-AF546$485 / 100μlE45R11316N-AF594$485 / 100μlE45R11316N-AF610$485 / 100μlE45R11316N-AF635$485 / 100μlE45R11316N-AF647$485 / 100μlE45R11316N-AF680$485 / 100μlE45R11316N-AF700$485 / 100μlE45R11316N-AF750$485 / 100μlE45R11316N-AF790$485 / 100μlE45R11316N-APC$485 / 100μlE45R11316N-PE$485 / 100μlE45R11316N-Cy3$485 / 100μlE45R11316N-Cy5$485 / 100μlE45R11316N-Cy5.5$485 / 100μlE45R11316N-Cy7$485 / 100μlE45R11316N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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Niemann Pick C1 Rabbit mAb | EnoGene Biotech Co. Ltd