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EXOSC7 Rabbit mAb
Human
$458/ 100 µl
QuantityTotal: $458
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5518550
TypeMonoclonal Antibodies
HostRabbit
Positive controlHepG2, A-431, K-562, U-251MG
IsotypeIgG
SummaryNon-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR and/or Ig variable region somatic hypermutation (SHM by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9 is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human EXOSC7.
PurificationAffinity purification
Gene ID23016
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
All Names
AlternameEXOSC7; EAP1; RRP42; Rrp42p; hRrp42p; p8; exosome component 7
Conjugated Antibody
This product is also available conjugated. Format: E45R11304N-Conjugate. Price: $485 / Size: 100μl.
E45R11304N-FITC$485 / 100μlE45R11304N-Biotin$485 / 100μlE45R11304N-HRP$485 / 100μlE45R11304N-AP$485 / 100μlE45R11304N-AF350$485 / 100μlE45R11304N-AF405M$485 / 100μlE45R11304N-AF488$485 / 100μlE45R11304N-AF514$485 / 100μlE45R11304N-AF532$485 / 100μlE45R11304N-AF555$485 / 100μlE45R11304N-AF568$485 / 100μlE45R11304N-AF405S$485 / 100μlE45R11304N-AF405L$485 / 100μlE45R11304N-AF546$485 / 100μlE45R11304N-AF594$485 / 100μlE45R11304N-AF610$485 / 100μlE45R11304N-AF635$485 / 100μlE45R11304N-AF647$485 / 100μlE45R11304N-AF680$485 / 100μlE45R11304N-AF700$485 / 100μlE45R11304N-AF750$485 / 100μlE45R11304N-AF790$485 / 100μlE45R11304N-APC$485 / 100μlE45R11304N-PE$485 / 100μlE45R11304N-Cy3$485 / 100μlE45R11304N-Cy5$485 / 100μlE45R11304N-Cy5.5$485 / 100μlE45R11304N-Cy7$485 / 100μlE45R11304N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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