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SARS-CoV-2 3CLpro Rabbit mAb

SARS-CoV-2
P0DTC2
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518532
TypeMonoclonal Antibodies
HostRabbit
Positive control293T
IsotypeIgG
Summary[Spike protein S1]: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein. Binding to host NRP1 and NRP2 via C-terminal polybasic sequence enhances virion entry into host cell. This interaction may explain virus tropism of human olfactory epithelium cells, which express high level of NRP1 and NRP2 but low level of ACE2. The stalk domain of S contains three hinges, giving the head unexpected orientational freedom. Uses human TMPRSS2 for priming in human lung cells which is an essential step for viral entry. Can be alternatively processed by host furin. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price458$
ImmunogenRecombinant fusion protein of SARS-CoV-2 3CLpro.
PurificationAffinity purification
Gene ID43740578
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

Conjugated Antibody

This product is also available conjugated. Format: E45R11286N-Conjugate. Price: $485 / Size: 100μl.

E45R11286N-FITC$485 / 100μlE45R11286N-Biotin$485 / 100μlE45R11286N-HRP$485 / 100μlE45R11286N-AP$485 / 100μlE45R11286N-AF350$485 / 100μlE45R11286N-AF405M$485 / 100μlE45R11286N-AF488$485 / 100μlE45R11286N-AF514$485 / 100μlE45R11286N-AF532$485 / 100μlE45R11286N-AF555$485 / 100μlE45R11286N-AF568$485 / 100μlE45R11286N-AF405S$485 / 100μlE45R11286N-AF405L$485 / 100μlE45R11286N-AF546$485 / 100μlE45R11286N-AF594$485 / 100μlE45R11286N-AF610$485 / 100μlE45R11286N-AF635$485 / 100μlE45R11286N-AF647$485 / 100μlE45R11286N-AF680$485 / 100μlE45R11286N-AF700$485 / 100μlE45R11286N-AF750$485 / 100μlE45R11286N-AF790$485 / 100μlE45R11286N-APC$485 / 100μlE45R11286N-PE$485 / 100μlE45R11286N-Cy3$485 / 100μlE45R11286N-Cy5$485 / 100μlE45R11286N-Cy5.5$485 / 100μlE45R11286N-Cy7$485 / 100μlE45R11286N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

SARS-CoV-2 3CLpro Rabbit mAb | EnoGene Biotech Co. Ltd