Product Information
Cite ID#EN5518507
TypeMonoclonal Antibodies
HostRabbit
Positive controlHL-60, THP-1, 293T, Mouse lung, Mouse spleen, Mouse heart, Rat lung
IsotypeIgG
SummaryThis gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.