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[KO Validated] GPX4 Rabbit mAb

E45R11241NDatasheetCOAMSDS
Human, Mouse, Rat
WB (Rattus norvegicus, Mus musculus)
P36969
$458/ 100 µl
Quantity
Total: $458

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5518487
TypeMonoclonal Antibodies
HostRabbit
Positive controlU-87MG, PC-3, Jurkat, Mouse kidney, Mouse heart, Rat kidney
IsotypeIgG
SummaryThe protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016]
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Price458$
ImmunogenA synthesized peptide derived from human GPX4
PurificationAffinity purification
Gene ID2879
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IP 1:50 - 1:200

All Names

AlternameGPx-4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R11241N-Conjugate. Price: $485 / Size: 100μl.

E45R11241N-FITC$485 / 100μlE45R11241N-Biotin$485 / 100μlE45R11241N-HRP$485 / 100μlE45R11241N-AP$485 / 100μlE45R11241N-AF350$485 / 100μlE45R11241N-AF405M$485 / 100μlE45R11241N-AF488$485 / 100μlE45R11241N-AF514$485 / 100μlE45R11241N-AF532$485 / 100μlE45R11241N-AF555$485 / 100μlE45R11241N-AF568$485 / 100μlE45R11241N-AF405S$485 / 100μlE45R11241N-AF405L$485 / 100μlE45R11241N-AF546$485 / 100μlE45R11241N-AF594$485 / 100μlE45R11241N-AF610$485 / 100μlE45R11241N-AF635$485 / 100μlE45R11241N-AF647$485 / 100μlE45R11241N-AF680$485 / 100μlE45R11241N-AF700$485 / 100μlE45R11241N-AF750$485 / 100μlE45R11241N-AF790$485 / 100μlE45R11241N-APC$485 / 100μlE45R11241N-PE$485 / 100μlE45R11241N-Cy3$485 / 100μlE45R11241N-Cy5$485 / 100μlE45R11241N-Cy5.5$485 / 100μlE45R11241N-Cy7$485 / 100μlE45R11241N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] GPX4 Rabbit mAb | EnoGene Biotech Co. Ltd