Catalog Number:
E45R07135G-1Amount:
100 µlCite ID#:
EN5481382Price:
395$Type:
Rabbit Polyclonal AntibodyHost:
RabbitReactivity:
MImmunogen:
This Mouse Pdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-414 amino acids from the C-terminal region of mouse Pdk3.Purification:
Affinity chromatography purified.Gene Name:
Pdk3Gene ID:
236900Swiss-Prot No.:
Q922H2Function:
Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).Form:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.Storage/Stability:
For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Applications:
WB, IHC-PDilution:
WB--1:1000Altername:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, Pdk3