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FOXN4 Antibody (N-term)
Datasheet   

  • Catalog Number:

    E45R03823G-1

  • Amount:

    100 µl

  • Cite ID#:

    EN5481104

  • Price:

    395$

  • Type:

    Rabbit Polyclonal Antibody

  • Host:

    Rabbit

  • Reactivity:

    H

  • Immunogen:

    This FOXN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human FOXN4.

  • Purification:

    Affinity chromatography purified.

  • Gene Name:

    FOXN4

  • Gene ID:

    121643

  • Swiss-Prot No.:

    Q96NZ1

  • Function:

    Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'- ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

  • Form:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

  • Storage/Stability:

    For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

  • Applications:

    WB

  • Dilution:

    WB--1:1000

  • Altername:

    Forkhead box protein N4, FOXN4

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  • Amount:100 µl
  • Price:395$

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FOXN4 Antibody (N-term) | EnoGene Biotech Co. Ltd