Catalog Number:
E45R03457G-4Amount:
50 µlCite ID#:
EN5469754Price:
295$Type:
Rabbit Polyclonal AntibodyHost:
RabbitReactivity:
H, MImmunogen:
This UBE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-445 amino acids from the C-terminal region of human UBE1C.Purification:
Affinity chromatography purified.Gene Name:
UBA3Gene ID:
9039Swiss-Prot No.:
Q8TBC4Function:
Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression.Summary:
Tissue Location:Form:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.Storage/Stability:
For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Applications:
WB, IHC-PDilution:
WB--1:1000Altername:
NEDD8-activating enzyme E1 catalytic subunit, 632-, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-activating enzyme 3, UBA3, UBE1CSynonyms:
NEDD8-activating enzyme E1 catalytic subunit, 632-, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-activating enzyme 3, UBA3, UBE1C