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phospho-LATS1-T1079/LATS2-T1041 Rabbit pAb

E45R01182NDatasheetCOAMSDS
Human, Mouse, Rat
O95835
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506610
TypePhosphorylated Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryThe protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA phospho specific peptide corresponding to residues surrounding T1079 of human LATS1.
PurificationAffinity purification
Gene ID9113/26524
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

All Names

AlternameLATS1; WARTS; wts
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R01182N-Conjugate. Price: $485 / Size: 100μl.

E45R01182N-FITC$485 / 100μlE45R01182N-Biotin$485 / 100μlE45R01182N-HRP$485 / 100μlE45R01182N-AP$485 / 100μlE45R01182N-AF350$485 / 100μlE45R01182N-AF405M$485 / 100μlE45R01182N-AF488$485 / 100μlE45R01182N-AF514$485 / 100μlE45R01182N-AF532$485 / 100μlE45R01182N-AF555$485 / 100μlE45R01182N-AF568$485 / 100μlE45R01182N-AF405S$485 / 100μlE45R01182N-AF405L$485 / 100μlE45R01182N-AF546$485 / 100μlE45R01182N-AF594$485 / 100μlE45R01182N-AF610$485 / 100μlE45R01182N-AF635$485 / 100μlE45R01182N-AF647$485 / 100μlE45R01182N-AF680$485 / 100μlE45R01182N-AF700$485 / 100μlE45R01182N-AF750$485 / 100μlE45R01182N-AF790$485 / 100μlE45R01182N-APC$485 / 100μlE45R01182N-PE$485 / 100μlE45R01182N-Cy3$485 / 100μlE45R01182N-Cy5$485 / 100μlE45R01182N-Cy5.5$485 / 100μlE45R01182N-Cy7$485 / 100μlE45R01182N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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phospho-LATS1-T1079/LATS2-T1041 Rabbit pAb | EnoGene Biotech Co. Ltd