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Phospho-RPS6KA5-S376 Rabbit pAb

E45R01083NDatasheetCOAMSDS
Human, Mouse, Rat
O75582
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506574
TypePhosphorylated Antibodies
HostRabbit
Positive controlNIH/3T3
IsotypeIgG
SummarySerine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes (PubMed:11909979). Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli (PubMed:11909979). Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression (PubMed:12628924). In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress (PubMed:12628924). In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential (PubMed:12763138). Phosphorylates ETV1/ER81 at 'Ser-191' and 'Ser-216', and thereby regulates its ability to stimulate transcription (PubMed:12569367). Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A (PubMed:15010469). Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA synthetic phosphorylated peptide around S376 of human RPS6KA5 (NP_004746.2).
PurificationAffinity purification
Gene ID9252
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:100

All Names

AlternameRPS6KA5; MSK1; MSPK1; RLPK
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R01083N-Conjugate. Price: $485 / Size: 100μl.

E45R01083N-FITC$485 / 100μlE45R01083N-Biotin$485 / 100μlE45R01083N-HRP$485 / 100μlE45R01083N-AP$485 / 100μlE45R01083N-AF350$485 / 100μlE45R01083N-AF405M$485 / 100μlE45R01083N-AF488$485 / 100μlE45R01083N-AF514$485 / 100μlE45R01083N-AF532$485 / 100μlE45R01083N-AF555$485 / 100μlE45R01083N-AF568$485 / 100μlE45R01083N-AF405S$485 / 100μlE45R01083N-AF405L$485 / 100μlE45R01083N-AF546$485 / 100μlE45R01083N-AF594$485 / 100μlE45R01083N-AF610$485 / 100μlE45R01083N-AF635$485 / 100μlE45R01083N-AF647$485 / 100μlE45R01083N-AF680$485 / 100μlE45R01083N-AF700$485 / 100μlE45R01083N-AF750$485 / 100μlE45R01083N-AF790$485 / 100μlE45R01083N-APC$485 / 100μlE45R01083N-PE$485 / 100μlE45R01083N-Cy3$485 / 100μlE45R01083N-Cy5$485 / 100μlE45R01083N-Cy5.5$485 / 100μlE45R01083N-Cy7$485 / 100μlE45R01083N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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Phospho-RPS6KA5-S376 Rabbit pAb | EnoGene Biotech Co. Ltd