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Phospho-TBC1D4-T642 Rabbit pAb

E45R01074NDatasheetCOAMSDS
Human, Mouse
O60343
$510/ 100 µl
Quantity
Total: $510

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506580
TypePhosphorylated Antibodies
HostRabbit
Positive control293T
IsotypeIgG
SummaryThis gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2), a calmodulin-binding domain (CBD), a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4), important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insulin, this protein is phosphorylated, dissociates from GLUT4 vesicles, resulting in increased GLUT4 at the cell surface, and enhanced glucose transport. Phosphorylation of this protein by AKT is required for proper translocation of GLUT4 to the cell surface. Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion. Alternative splicing results in multiple transcript variants encoding different isoforms.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenA synthetic phosphorylated peptide around T642 of human TBC1D4 (NP_055647.2).
PurificationAffinity purification
Gene ID9882
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameAS160; NIDDM5; TBC1D4
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R01074N-Conjugate. Price: $485 / Size: 100μl.

E45R01074N-FITC$485 / 100μlE45R01074N-Biotin$485 / 100μlE45R01074N-HRP$485 / 100μlE45R01074N-AP$485 / 100μlE45R01074N-AF350$485 / 100μlE45R01074N-AF405M$485 / 100μlE45R01074N-AF488$485 / 100μlE45R01074N-AF514$485 / 100μlE45R01074N-AF532$485 / 100μlE45R01074N-AF555$485 / 100μlE45R01074N-AF568$485 / 100μlE45R01074N-AF405S$485 / 100μlE45R01074N-AF405L$485 / 100μlE45R01074N-AF546$485 / 100μlE45R01074N-AF594$485 / 100μlE45R01074N-AF610$485 / 100μlE45R01074N-AF635$485 / 100μlE45R01074N-AF647$485 / 100μlE45R01074N-AF680$485 / 100μlE45R01074N-AF700$485 / 100μlE45R01074N-AF750$485 / 100μlE45R01074N-AF790$485 / 100μlE45R01074N-APC$485 / 100μlE45R01074N-PE$485 / 100μlE45R01074N-Cy3$485 / 100μlE45R01074N-Cy5$485 / 100μlE45R01074N-Cy5.5$485 / 100μlE45R01074N-Cy7$485 / 100μlE45R01074N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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Phospho-TBC1D4-T642 Rabbit pAb | EnoGene Biotech Co. Ltd