Catalog Number:
E45M22164G-4Amount:
50 µlCite ID#:
EN5476377Price:
295$Type:
Mouse Monoclonal AntibodyHost:
MouseReactivity:
HImmunogen:
This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK.Purification:
Affinity chromatography purified.Gene Name:
MAFKGene ID:
7975Swiss-Prot No.:
O60675Function:
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:9150357). However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites (PubMed:9150357, PubMed:8932385). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (PubMed:9150357).Storage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB, FCDilution:
FC--1:25Altername:
Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit, MAFK