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PKA C-alpha (PRKACA) Mouse mAb
Human, Mouse, Rat
$510/ 100 µl
QuantityTotal: $510
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5516827
TypeMonoclonal Antibodies
HostMouse
Positive controlHeLa, PC-3, C6, Mouse testis, Mouse brain, Rat testis
IsotypeIgG
SummaryThis gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price510$
ImmunogenRecombinant protein of human PKA C-alpha (PKA C-alpha (PRKACA)).
PurificationAffinity purification
Gene ID5566
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternamePRKACA; PKACA; PPNAD4; cAMP-dependent protein kinase catalytic subunit alpha
Conjugated Antibody
This product is also available conjugated. Format: E45M22063N-Conjugate. Price: $485 / Size: 100μl.
E45M22063N-FITC$485 / 100μlE45M22063N-Biotin$485 / 100μlE45M22063N-HRP$485 / 100μlE45M22063N-AP$485 / 100μlE45M22063N-AF350$485 / 100μlE45M22063N-AF405M$485 / 100μlE45M22063N-AF488$485 / 100μlE45M22063N-AF514$485 / 100μlE45M22063N-AF532$485 / 100μlE45M22063N-AF555$485 / 100μlE45M22063N-AF568$485 / 100μlE45M22063N-AF405S$485 / 100μlE45M22063N-AF405L$485 / 100μlE45M22063N-AF546$485 / 100μlE45M22063N-AF594$485 / 100μlE45M22063N-AF610$485 / 100μlE45M22063N-AF635$485 / 100μlE45M22063N-AF647$485 / 100μlE45M22063N-AF680$485 / 100μlE45M22063N-AF700$485 / 100μlE45M22063N-AF750$485 / 100μlE45M22063N-AF790$485 / 100μlE45M22063N-APC$485 / 100μlE45M22063N-PE$485 / 100μlE45M22063N-Cy3$485 / 100μlE45M22063N-Cy5$485 / 100μlE45M22063N-Cy5.5$485 / 100μlE45M22063N-Cy7$485 / 100μlE45M22063N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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