Catalog Number:
E45M22008V-2Amount:
50 ulCite ID#:
EN5458163Price:
255$Type:
Mouse Monoclonal AntibodyResearch Field:
Cytokine-cytokine receptor interactionProduct Description:
OX40(TNFRSF4) mouse monoclonal antibody,clone UMLBI276Host:
MouseReactivity:
HumanImmunogen:
Full length human recombinant protein of human TNFRSF4 (NP_003318) produced in HEK293T cell.Target:
TNFRSF4Clone Number:
UMClone 276Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
Homo sapiens TNF receptor superfamily member 4 (TNFRSF4), mRNA.Gene symbol:
TNFRSF4Gene ID:
7293Swiss-Prot No.:
P43489Pathway:
Cytokine-cytokine receptor interactionFunction:
TransmembraneSummary:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
0.5~1.0 mg/ml (Lot Dependent)Storage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
IHC 1:100~300Synonyms:
ACT35; CD134; IMD16; OX40; TXGP1L