AMACR Mouse Monoclonal Antibody [Clone UMLBI215]
Datasheet
Catalog Number:
E45M21951V-2Amount:
50 ulCite ID#:
EN5458106Price:
255$Type:
Mouse Monoclonal AntibodyResearch Field:
Metabolic pathways, Primary bile acid biosynthesisProduct Description:
AMACR mouse monoclonal antibody,clone UMLBI215Host:
MouseReactivity:
HumanImmunogen:
Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.Target:
AMACRClone Number:
UMClone 215Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, mRNA.Gene symbol:
AMACRGene ID:
23600Swiss-Prot No.:
Q9UHK6Pathway:
Metabolic pathways, Primary bile acid biosynthesisFunction:
Druggable GenomeSummary:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
0.5~1.0 mg/ml (Lot Dependent)Storage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
IHC 1:100~800Synonyms:
AMACRD; CBAS4; P504S; RACE; RM
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Catalog Number
- Amount:50 ul
- Price:255$
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