Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone 3F8]
Datasheet
Catalog Number:
E45M21485V-2Amount:
50 ulCite ID#:
EN5457640Price:
195$Type:
Mouse Monoclonal AntibodyResearch Field:
Amyotrophic lateral sclerosis (ALS)Product Description:
NEFL mouse monoclonal antibody, Clone 3F8Host:
MouseReactivity:
HumanImmunogen:
Human recombinant protein fragment corresponding to amino acids 401-543aa of human NEFL (NP_006149) produced in E.coli.Target:
NEFLClone Number:
Clone 3F8Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
neurofilament, light polypeptideGene symbol:
NEFLGene ID:
4747Swiss-Prot No.:
P07196Pathway:
Amyotrophic lateral sclerosis (ALS)Function:
Druggable Genome, ES Cell Differentiation/IPSSummary:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
ELISA 1:5000-10000Synonyms:
CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110
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Catalog Number
- Amount:50 ul
- Price:195$
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