Catalog Number:
E45M18848V-2Amount:
50 ulCite ID#:
EN5455003Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
ESRRA mouse monoclonal antibody,Clone 3G3Host:
MouseReactivity:
HumanImmunogen:
Human recombinant protein fragment corresponding to amino acids 206-417 of human ESRRA (NP_004442) produced in E.coli.Target:
ESRRAClone Number:
Clone 3G3Isotype:
IgG2aPurification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
estrogen related receptor alphaGene symbol:
ESRRAGene ID:
2101Swiss-Prot No.:
P11474Function:
Druggable Genome, Nuclear Hormone Receptor, Transcription FactorsSummary:
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:500~2000Synonyms:
ERR1; ERRa; ERRalpha; ESRL1; NR3B1