Pepsinogen II (PGC) Mouse Monoclonal Antibody [Clone 1H5]
Datasheet
Catalog Number:
E45M18806V-2Amount:
50 ulCite ID#:
EN5454961Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
PGII mouse monoclonal antibody,Clone 1H5Host:
MouseReactivity:
HumanImmunogen:
Native Human Pepsinogen II proteinTarget:
PGCClone Number:
Clone 1H5Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
progastricsin (pepsinogen C)Gene symbol:
PGCGene ID:
5225Swiss-Prot No.:
P20142Function:
Protease, Secreted ProteinSummary:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
1:100 - 1:1000Synonyms:
PEPC; PGII
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Catalog Number
- Amount:50 ul
- Price:195$
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