Catalog Number:
E45M15333V-2Amount:
50 ulCite ID#:
EN5451488Price:
195$Type:
Mouse Monoclonal AntibodyResearch Field:
Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathwayProduct Description:
CD4 mouse monoclonal antibody, Clone 1D1Host:
MouseReactivity:
HumanImmunogen:
Full length human recombinant protein of human CD4 (NP_000607) produced in HEK293T cell.Target:
CD4Clone Number:
Clone 1D1Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
CD4 moleculeGene symbol:
CD4Gene ID:
920Swiss-Prot No.:
P01730Pathway:
Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathwayFunction:
Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, TransmembraneSummary:
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:2000Synonyms:
CD4mut; IMD79; OKT4D