Catalog Number:
E45M15049V-2Amount:
50 ulCite ID#:
EN5451204Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
KLK8 mouse monoclonal antibody, Clone 1A2Host:
MouseReactivity:
HumanImmunogen:
Human recombinant protein fragment corresponding to amino acids 33-260 of human KLK8 (NP_009127) produced in E.coli.Target:
KLK8Clone Number:
Clone 1A2Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
kallikrein related peptidase 8Gene symbol:
KLK8Gene ID:
11202Swiss-Prot No.:
O60259Function:
Druggable Genome, Secreted Protein, TransmembraneSummary:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq, JulForm:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
1 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:2000Synonyms:
HNP; NP; NRPN; PRSS19; TADG14