Catalog Number:
E45M11574V-2Amount:
50 ulCite ID#:
EN5447729Price:
195$Type:
Mouse Monoclonal AntibodyProduct Description:
SIRT5 mouse monoclonal antibody, Clone 2A11Host:
MouseReactivity:
Human, Mouse, RatImmunogen:
Full length human recombinant protein of human SIRT5(NP_036373) produced in HEK293 cell.Target:
SIRT5Clone Number:
Clone 2A11Isotype:
IgG1Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Gene Name:
sirtuin 5Gene symbol:
SIRT5Gene ID:
23408Swiss-Prot No.:
Q9NXA8Function:
Druggable Genome, Transcription FactorsSummary:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]Form:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Concentration:
0.41 mg/mlStorage/Stability:
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Applications:
WB 1:500, IHC 1:150, IF 1:50~100, FLOW 1:100Synonyms:
SIR2L5